IUI data with or without ovulation induction or super-ovulation are not required to be submitted to the federal government. There is a paucity of data on how diligent clinics are with their non IVF treatment. Paradoxically clinics that give a less than a full faith effort to non IVF treatment are “rewarded” with patients are more “successful” with IVF treatment.
In 2008 we reviewed our IUI cycles from 2000 to 2007 to study the impact of low sperm morphology on pregnancy outcome. We presented our data at the 2008 Annual Meeting of the American Society for Reproductive Medicine (Abstract 650765). Below is a summary of our IUI data. The study showed:
- 1. The likelihood of pregnancy, about 16-21% per cycle, does not seem to be affected by the percentage of normal sperm morphology by Kruger strict criteria.
- 2. There is a slight but non significant statistically trend towards more miscarriage among women whose partners have less than 5% normal morphology by Kruger criteria. Live birth rate per cycle was 15% but dropped to 11% if normal sperm morphology was 4% or less.
% Normal Sperm Morphology % Women Live Birth % Cycles Live Birth # women # Cycles Live Births ≤4% 26 11 87 219 23 5-13% 35 15 207 484 73 ≥14% 39 15 66 177 26 360 880 122
- 3. The likelihood of a successful live birth with IUI declines significantly after three to four cycles of IUI, consistent with other studies on IUI success.